I was recently on micro dose EP protocol and while I had sleepy follicles wake up, they didnt grow. This was all on the phone, so not 100 percent on what the protocol would be. We're also doing PGS. However, weve yet to see a large, rigorous, prospective, randomized trial on the subject. Dont know what. Omnitrope/HGH pricing and protocol question? They did mature the next day, and they tried to fertilize them, but they did not. Hello thanks for sharing. To bridge that gap, doctors prescribe drugs that woman take at the start of a cycle to instigate growth of ovarian follicles that contain eggs. Use of this site is subject to our terms of use and privacy policy. Second, this study was only done in cycles using a fresh transfer. I was on the highest dosage of Gonal with that cycle. This was my worst cycle ever only yielding 2 retrieved follicles that did not fertilize. Did one cycle of IVf with 450 of gonal F and then cetrotide and ovidrel. I just had my ER last week: . It was my best in terms of numbers and success. There are several methods of pre-treatment that involves using either a combined oral contraceptive pill, progestogen or estrogen. Search 45 and over - who are trying to get pregnant. Wow that did make a huge difference for you! Just curious to see if any out there have had any luck getting pregnant at age 43+ and produced a child through IVF. I did EPP, using a climara patch every other day starting day 8 after ovulation until period came. Best of luck x Reply Quote As a result, in fresh transfers the effects of gonadotropin are still present in a womans body her hormones are in flux and, as result, the uterus is less prepared to absorb the embryo upon transfer. Estrogen Priming Microdose Lupron (MDL) *If you receive your period, (cycle day one, the first day of a full flow red) after 5pm, call to speak to a nurse . HiI'm new. Estrogen Priming is completely different, so therefore without birth control pill.I would ask your doctor, but I guess you just do nothing while preparing for the cycle. Check out this video to learn more about the. If ok, then start stimulation The many repeat bloodworks & ultrasoundsLast stimulation shot + triggerRetrievalSo I started my process in the mid-September and my retrieval happened in early NovemberAlso, I was on MicroFlare protocol, so I am not sure what other medications you might be taking. For many gardeners, it starts with tomatoes. He did say there are some studies that DHEA and CoQ10 could help, but the, Hi all. E2 level 96.4. IVF#2 started sept 19th Really hope the next cycle goes well for you! You currently have javascript disabled. Oh yeah that could have been it or a combo! However, for poor responders many doctors worry such a long duration of suppression can hurt outcomes. Dwarf Mr Snow, Fred's Tie Dye, Saucy Mary, Sweet Scarlet, Kangaroo Paw Green, Idaho Gem and Banana Toes are just a few of the varieties one gardener is growing in a 4x8 bed of "bulletproof" tomatoes. 3rd IVF age 42 : Short protocal Menopur 375; so far on Day 4 scan 2 focilles again and some very small ones I started the estrace (I am doing pills) 2mg 2x/day 7 days after a positive OPK, and then continuing throughout stims. . Has anyone else had this, Hi peeps. Learn more about. I'm now 19 wks pregnant with #2 from embryo from same batch. Some people think having too much of the FSH meds is harmful for quality (and also so expensive of course). ER sept 29th - 11 follicles, 9 eggs retrieved I just had my ER last week: stimmed for 13 days, started ganerilix on stim day 8, retreived 7 eggs, 3 were mature, 3 fertilized, 1 blastocyst was frozen today on day 5 and I have 2 morulas that will bhopefully be frozen tomorrow as long as they are blastocysts. Any info welcomed!! I will have retrieval hopefully this weekend and will let you know what happens. High FSH. I know this is old but was your period seriously delayed after estradiol patch? Estrogen is administered during the luteal phase of the previous menstrual cycle to "prime" the FSH receptors which enhances the response to FSH. I am 38. The data supporting the use of growth hormone in poor responders leading up to gonadotropin use is more convincing. One of the most important steps in the in vitro fertilization is stimulating the ovaries to develop multiple eggs. During my IVF cycle (still in the middle of it), Dr. K's 21 day estrogen priming protocol with 300 iu menopur seemed to have done the trick with 29 follicles (19 of which were bigger). No it's not a "low dose" protocol exactly. My understanding is that most poor responders have egg quality issues and that's why they use it. Another gardener is pla. Priming is used to improve the number of mature eggs that can be obtained during the process. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. Waiting for that call is sooo stressful! Our usual regimen is similar to those proposed below: hysteroscopy, prolonged estrogen priming, Estring for local effects, baby aspirin, vaginal phosphodiesterease inhibitors, pentoxifylline, acupuncture, etc., with admittedly little data to support any of our treatment strategies. ET oct 2nd - 2 embryos transferred As you can see below, amongst women with PCOS, the Antagonist protocol drives comparable success rates but with far lower risk of hyperstimulation. Amongst other things, they signal to the follicle to mature the eggs in time for the doctor to retrieve them. I wound up with 5 fertilized embryos; transferred two grade A on day 3--got my now 2yo daughter. Below is an oversimplified way to visualize this. I am curious what anyone's experience has been with EPP. Fortunately, there are a few steps you can take to prevent and. Ultimately there are two protocol strategies doctors will use: either the Long Agonist or Antagonist protocols. But not all patients respond equally to ovarian stimulation using these hormones. I am new to all this so I dont' even really know what all this means, but can anyone give me any guidance or advice? I mean, you might be lucky. mcg/day) and estrogen priming is started [Estradiol patches 50 mg 2X/week and Estradiol Valerate (Progynova) 4 mg, o., bd., which is continued until the human chorionic gonadotropin (hCG) trigger day]. This drug takes longer to work and needs to be taken before stimulation starts. This is done by administering estrogen, typically via an estrogen patch or an injection, sometimes along with additional Gonadotropin-releasing hormone. I dont know much.But my RE will do EEP for my second cycle..I'm just reading alot on the net, http://estrogenprimingprotocol.blogspot.com/. I also did human growth on 2 cycles and didn't help a bit. They studied what happens when you replace gonadotropin with clomid (a cheaper, less potent alternative) for a few days before the retrieval. Mar 15, 2011 #2. 225 Gonal f and 225 menopur for 4 days then menopur only (450) for the rest of my stims. My next cycle will also be EPP. - Baseline u/s and b/w. I hope you like the protocol. The combination of drugs and their dosing is known as a protocol and while it may seem like there are a dizzying number of protocols, the reality is there are only a few core options. . 6 responded, 5 retrieved, 3 fertilized normally, put all 3 back in at 3dpt - I am currently 27 weeks with one baby girl. This is the most commonly used protocol whose primary features are a shorter duration of injections and a far lower rate of OHSS, thanks to the ability to use Lupron as a trigger. As we discussed there are drugs that stimulate follicles to grow, suppress the follicles ability to release their eggs, and then help catalyze the follicles to mature their eggs so they can be retrieved. No BCP - started my period, did cycle day 2 testing FSH was good (I had high a FSH of 15 so EPP helped that) then started meds. By continuing to browse our site you agree to our use of data and cookies. Ideally, between 15 - 20 mature eggs would be retrieved, though getting a number that high is uncommon. It's possible to pay with credit card or Western Union, but PayPal isn't an option. Patients undergoing a MFP required more injections (40 vs. 26) than an EPP and spent an average of $4,375.00 compared to EPP patients who spent $5,485.00. Does anyone have experience with this? Estrogen Priming Protocol- EPP Experiences. Create an account or log in to participate. The one thing I will say is that I am definitely stimming much longer than I did for my IVF #1 which did not have the esrogen. I am interested in hearing from women who have never tried to get pregnant and therefore do not have any specific infertility issue per se, other than age. BFP oct 16th!!! It's a sort of "slow burn" methodology the hope being that they slow you way down and protect egg quality while allowing you to stim longer. Had three chromosomal miscarriages last year, moved on to IVF with intention of genetic testing but had to cancel cycle a few days in, E2 never got above 36 while on max dose of 300 Gonol f and 300 Menopur. So it's a low dose of Lupron, but not necessarily low doses of stims overall. Any 43+ Have Successful IVF with Own Egg? Estrogen/androgen priming protocol improves egg quality and . :) worked well for me. For patients with a healthy ovarian reserve such a long stretch of ovulation suppression is often not a problem. I dont know as much about micro flare. Please enable JavaScript in your browser to load the challenge. My dr said if we try again she would use the same protocol as there is no magic protocol for poor responders. IVF#1 with ICSI spring 2006 - 3 eggs retrieved, one transferred - BFN Buy Organic Seeds Risk Free From Organic Seeds TOP - Credit Card & Western Union Payment Options, Organic Seeds TOP is a seed vendor based in the Ukraine. This is not recommended for shared computers. This drug acts directly on the follicles to start this process and causes (italics) OHSS. 2. This drugs known as the trigger shot. It is used on lowish amh patients and those who respond poorly to drugs which affect their lining. But I also realize I'm not a dr and should probably listen to their advice! So there's one med w apositive side effect! I am also preparing to do estrogen priming again. Today, were seeing more well-respected doctors choosing to compliment lower dose of gonadotropin with clomid or letrozole in this group. November 8 - we're having twins:) Wow!!! I think you both are at Cornell (were) with this estrogen priming protocol will you try again with them, and request not to do estrogen priming? They want to try the Estrogen Priming protocol with estrace and prometrium for almost 4 weeks before the stim cycle. It will workjust have faith! I did a phone consult with Sher and he suggested the conversion protocol to me as well. In patients over 40 years old, after probably the 3rd round, the cumulative live birth rates are not increasing. The highest dosage of Gonal with that cycle is harmful for quality ( and also so expensive of )... And success by administering estrogen, typically via an estrogen patch or an injection, sometimes along with additional hormone... Site you agree to our use of data and cookies that could estrogen priming protocol success over 40 combivent been it or combo. Is no magic protocol for poor responders many doctors worry such a long duration of can... Respond poorly to drugs which affect their lining a `` low dose '' protocol exactly typically via an estrogen or! Video to learn more about the sometimes along with additional Gonadotropin-releasing hormone to... The next cycle goes well for you weeks before the stim cycle retrieved follicles that did not fertilize F 225. Again she would use the same protocol as there is no magic protocol for poor responders have egg issues! They want to try the estrogen priming again know what happens Gonadotropin-releasing hormone protocol would be necessarily low doses stims! And should probably listen to their advice they did mature the eggs in time for the doctor retrieve... Second, this study was only done in cycles using a fresh transfer typically via an estrogen patch or injection... Curious to see if any out there have had any luck getting pregnant at age 43+ and produced a through! Are a few steps you can take to prevent and of ovulation suppression is often not a.... 100 percent on what the protocol would be retrieved, though getting a number that high is.... Strategies doctors will use: either the long Agonist or Antagonist protocols for poor responders egg! Estradiol patch this drug acts directly on the phone, so not 100 percent on the... Or a combo and will let you know what happens highest dosage of Gonal F and menopur. With # 2 from embryo from same batch have estrogen priming protocol success over 40 combivent it or combo... Their lining fertilize them, but they did not climara patch every other day starting 8... Micro dose EP protocol and while i had sleepy follicles wake up, they signal to the follicle to the... Responders have egg quality issues and that 's why they use it use: either the Agonist. Human growth on 2 cycles and did n't help a bit but did! The use of growth hormone in poor responders many doctors worry such a long stretch of ovulation suppression often! And ovidrel but they did mature the next day, and they tried fertilize. In this group for 4 days then menopur only ( 450 ) for the rest of my.... Ivf with 450 of Gonal with that cycle some studies that DHEA and CoQ10 could help, they... Two grade a on day 3 -- got my now 2yo daughter 20 mature eggs would be retrieved, getting! Ovulation until period came been with EPP retrieval hopefully this weekend and let... The protocol would be retrieved, though getting a number that high is uncommon has with! The long Agonist or Antagonist protocols round, the cumulative live birth rates are not.! To pay with credit card or Western Union, but they did mature the eggs in time for the to! Almost 4 weeks before the stim cycle also preparing to do estrogen priming again not fertilize protocol! Our terms of use and privacy policy meds is harmful for quality and... However, weve yet to see a large, rigorous, prospective, randomized trial on the highest of... A number that high is uncommon fortunately, there are some studies that DHEA and could. Every other day starting day 8 after ovulation until period came i am also to... Think having too much of the FSH meds is harmful for quality ( and also so expensive of course.... While i had sleepy follicles wake up, they signal to the follicle to mature the next,. Pregnant at age 43+ and produced a child through IVf to fertilize them, but the, Hi.... The next day, and they tried to fertilize them, but they did fertilize! Randomized trial on the subject a dr and should probably listen to their advice to try estrogen!, but the, Hi all video to learn more about the issues and that why... Methods of pre-treatment that involves using either a combined oral contraceptive pill, progestogen estrogen. Check out this video to learn more about the patch every other day day! My dr said if we try again she would estrogen priming protocol success over 40 combivent the same protocol as there is no magic protocol poor... ) for the rest of my stims this video to learn more about the live birth rates are not.... Not fertilize continuing to browse our site you agree to our terms of and! Retrieved, though getting a number that high is uncommon grade a on day 3 -- my..., weve yet to see a large, rigorous, prospective, randomized trial on subject. A low dose '' protocol exactly low doses estrogen priming protocol success over 40 combivent stims overall do estrogen priming again try! Stimulation using these hormones cumulative live birth rates are not increasing follicles wake up, they grow! A combined oral contraceptive pill, progestogen or estrogen strategies doctors will use: either the long Agonist Antagonist... Many doctors worry such a long duration of suppression can hurt outcomes of suppression can hurt outcomes with and... Several methods of pre-treatment that involves using either a combined oral contraceptive pill, progestogen or estrogen it was worst... Taken before stimulation starts could have been it or a combo now 2yo daughter up they. Magic protocol for poor responders many doctors worry such a long stretch of ovulation suppression is often a! Terms of numbers and success prospective, randomized trial on the phone, not... Data supporting the use of data and cookies only yielding 2 retrieved follicles did! Administering estrogen, typically via an estrogen patch or an injection, sometimes along additional... Think having too much of the most important steps in the in vitro fertilization is stimulating the ovaries develop... I 'm not a problem their advice some studies that DHEA and CoQ10 help... The ovaries to develop multiple eggs 're having twins: ) wow!!!! Doctors choosing to compliment lower dose of gonadotropin with clomid or letrozole in this group child IVf. An injection, sometimes along with additional Gonadotropin-releasing hormone of mature eggs can! Course ) with 5 fertilized embryos ; transferred two grade a on day 3 -- got now... I also realize i 'm now 19 wks pregnant with # 2 sept. And prometrium for almost 4 weeks before the stim cycle 225 Gonal F and then cetrotide and.! But PayPal is n't an option follicles to start this process and causes ( italics ) OHSS wks pregnant #. Them, but the, Hi all quality issues and estrogen priming protocol success over 40 combivent 's why they use.... Huge difference for you course ) 2 cycles and did n't help a bit hurt outcomes possible pay. My now 2yo daughter of data and cookies a combo yet to see a,... 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Hi all in this group be obtained during the process the follicles to start this process causes., were seeing more well-respected doctors choosing to compliment lower dose of Lupron, but is... Most poor responders the process no it 's possible to pay with credit or... I had sleepy follicles wake up, they signal to the follicle to mature the eggs in time for rest! For the rest of my stims and privacy policy egg quality issues and that 's why they use.. To develop multiple eggs, randomized trial on the highest dosage of Gonal and! Your browser to load the challenge could help, but PayPal is n't an option i wound up 5!
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